Daniel G. Amen, MD

Dr. Daniel Amen is a double board-certified psychiatrist, 20-time national bestselling author, and one of the most influential voices in brain health. He’s the founder of Amen Clinics, home to the world’s largest database of brain scans related to behavior, with over 300,000 scans and counting.

Through his groundbreaking research, bestselling books, and BrainMD’s doctor-developed supplements, Dr. Amen has helped millions improve their memory, mood, focus, and mental well-being.

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Third-Party Tested

#1 Brand for Brain Health

Informed by 300,000+ Brain Scans

BEST VALUE

Third-Party Tested

#1 Brand for Brain Health

Informed by 300,000+ Brain Scans

BEST VALUE

Third-Party Tested

#1 Brand for Brain Health

Informed by 300,000+ Brain Scans

BEST VALUE

Third-Party Tested

#1 Brand for Brain Health

Informed by 300,000+ Brain Scans

BEST VALUE

Third-Party Tested

#1 Brand for Brain Health

Informed by 300,000+ Brain Scans

BEST VALUE

Third-Party Tested

#1 Brand for Brain Health

Informed by 300,000+ Brain Scans

BEST VALUE

Third-Party Tested

#1 Brand for Brain Health

Informed by 300,000+ Brain Scans

BEST VALUE

Third-Party Tested

#1 Brand for Brain Health

Informed by 300,000+ Brain Scans

BEST VALUE

Third-Party Tested

#1 Brand for Brain Health

Informed by 300,000+ Brain Scans

BEST VALUE

Third-Party Tested

#1 Brand for Brain Health

Informed by 300,000+ Brain Scans

BEST VALUE

Supported by Clinical Research


Happy Saffron Plus combines clinically studied ingredients, including saffron extract, curcumin, and zinc, selected for their roles in supporting emotional balance, cognitive health, memory, focus, and overall brain wellness. Research suggests these ingredients may help promote a positive mood, calm feelings, healthy thinking, and mental clarity through evidence-backed nutritional support.


Clinical studies have shown that saffron extract may help support a positive mood and emotional well-being. Human trials have explored saffron’s role in promoting a balanced emotional state and supporting overall mood health.

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Before

After

 
 

Lifestyle TipsFor Body & Mind

Serotonin is a key component in energylevels, emotional balance, and focus.You can help serotonin production bygetting some sun, exercising, journaling,yoga, meditation, or visualization exercises.
You can also take supplements to helpincrease your serotonin levels. Whilethe science on these supplements isrelatively new, there are some promising data supporting their benefits.

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What To Expect

94%

Clinical research shows that 400 mg of Longvida® curcumin—the same amount used in Happy Saffron Plus®—can boost working memory by 16% within just one hour of your first dose.

95%

In just 4 weeks, 28 mg/day of affron® saffron helped improve mood and sleep, and reduced stress by 41% in clinical trials.

99%

In 12 weeks, 28 mg/day of affron® saffron significantly improved mental health, reduced occasional anxiousness by 33% and low mood by 32%.

98%

Expect better mood, memory, and sexual health with continued use.

98%

Noticed that this product has significantly improved their life.

  • For Brain Health


    Backed by 30+ years of research, 60+ MDs & 300,000+ brain scans.*

  • Doctor-Recommended

    Formulated by Dr. Daniel Amen and leading brain health experts.

  • Clinically Backed


    Clinically studied ingredients. Backed by science. Proven to work.

  • HSA/FSA Eligible


    Use pre-tax dollars to support your brain, body, and daily health.

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      Hear It From Real Customers

        FAQs

        HOW DO I TAKE HAPPY SAFFRONPLUSR?

        It’s recommended that adults take 3 capsules daily between meals.

        CAN CHILDREN TAKE HAPPY SAFFRONPLUSR?

        Children ages 4-18 years can take 1 capsule per 40 pounds body weight, maximum 3 capsules daily.

        IS HAPPY SAFFRON PLUSR SUITABLEFOR VEGANS?

        Yes. Happy Saffron Plus® is suitable for vegans, especially those seeking to improve their mood.

        DOES THIS SUPPLEMENT CONTAINALLERGENS?

        It is free from dairy, gluten, sugar, corn, nuts, eggs, yeast, and artificial flavorings or colorings.* It does contain very small levels of soy (non-GMO).